Personal monitoring of cutaneous vitamin D3 production through a printable UV molecular dosimeter

Authors

  • Elaine Cavalcanti Rodrigues Vaz https://orcid.org/0000-0003-1764-5289
  • Thiago Domingues Universidade Federal de Pernambuco (UFPE), Centro de Informática (Cin)
  • Thayná Emilly Cavalcante Santos Universidade Federal de Pernambuco (UFPE), Centro de Informática (Cin)
  • Leandro Moura Universidade Federal de Pernambuco (UFPE), Centro de Informática (Cin)
  • Thalisson Tavares Universidade Federal de Pernambuco (UFPE), Centro de Informática (Cin)
  • Lúcio Flávio Melo Universidade Federal de Pernambuco (UFPE), Centro de Informática (Cin)
  • Diogo Henriques Universidade Federal de Pernambuco (UFPE), Centro de Informática (Cin)
  • Silvo de Barros Melo Universidade Federal de Pernambuco (UFPE), Centro de Informática (Cin) https://orcid.org/0000-0001-8600-6427
  • Petrus Santa-Cruz Universidade Federal de Pernambuco https://orcid.org/0000-0003-2475-7764

DOI:

https://doi.org/10.15392/bjrs.v10i2A.2032

Keywords:

printable dosimeter, UV molecular dosimetry, vitamin D3, personal dosimetry

Abstract

Cutaneous production of vitamin D by exposure of the skin to solar radiation can provide more than 90% of the daily dose needed by the human body, thanks to the range of UV radiation covered by its spectrum and may be the best option to reduce oral supplementation. The process can be monitored by personal UV dosimetry since this is the range of solar radiation related to its production. Aiming to monitor UVB dose looking for correlation with skin production of vitamin D3, a printed strip with the molecular dosimetry device was used to produce a photonic signal as input for calculations in software developed here to run on a smartphone. For this, the molecular dosimeter Eu(btfa)3·bipy was prepared to be printed as a functional ink with a MEMS-based Drop-on-Demand Dimatix DMP2831 Materials Printer to produce the functional paper strips.  To use our personal UV molecular dosimeter photonic signal as input data, a correlation curve must be established to convert the UV dose into the amount of vitamin D3 produced. There is a promising solution for personal monitoring of cutaneous vitamin D production by printable UV dosimeter targets, aiming to contribute to a better immune response of individuals. In addition, the creation of a cloud data lake capable of mapping population data on vitamin D deficiency can help define public health policies.

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Author Biographies

  • Thiago Domingues, Universidade Federal de Pernambuco (UFPE), Centro de Informática (Cin)

    Computer Science PhD student at CIn-UFPE (Centro de Informática - Universidade Federal de Pernambuco)

  • Silvo de Barros Melo, Universidade Federal de Pernambuco (UFPE), Centro de Informática (Cin)

    Professor Associado 3 do Centro de Informática da Universidade Federal de Pernambuco. Doutor em Computer Science pela Arizona State University (1998).

  • Petrus Santa-Cruz, Universidade Federal de Pernambuco

    Full Professor of the Department of Fundamental Chemistry at the Federal University of Pernambuco, PhD in Materials Science / Chemistry by - Université de Paris Sud (1995) and Productivity Fellow 1D in Technological Development and Innovative Extension of CNPq. He is Project Coordinator of the Program to Combat Epidemics (CAPES, call 09/2020), Coordinator of the SibratecNANO Project (MCTI/CNPq), in partnership with a company. He is also a member of the Coordination Center of the Innovation Center Network in Nanodevices and Nanosensors of the SIBRATEC system (MCTIC). He is responsible for the company Ponto Quântico Nanodispositivos, Innovation hub/technology-based company in the Innovation Space of UFPE (Positiva) and the LandFoton Laboratory (DQF/UFPE) and the Leader of the GrandFoton Research Group (DGP/CNPq).

References

DROR A.A.; MOROZOV N.; DAOUD A.; NAMIR Y.; YAKIR O.; SHACHAR Y. et al. Pre-infection 25-hydroxyvitamin D3 levels and association with severity of COVID-19 illness. PLOS ONE, 17(2): e0263069, 2022. DOI: https://doi.org/10.1371/journal.pone.0263069

GAMEIRO, C. G.; SILVA JÚNIOR, E. F.; ACHETE, C. A.; SIMAO, R. A.; SANTA-CRUZ, P. A. UV personal Dosimeters of lanthanide complex films: a new molecular photonic device characterized by AFM. In: The 13th International Conference on Solid State Dosimetry, 2001, Atenas. Proc. SSD 2001. Ashford: Nuclear Technology publishing, 2001. v. 1. p. 37.

SOUSA, F.L.N.; MOJICA-SÁNCHEZ, L.C.; GAVAZZA, S.; FLORENCIO, L.; VAZ, E.C.R.; SANTA-CRUZ, P.A. Printable UV personal dosimeter: sensitivity as a function of DoD parameters and number of layers of a functional photonic ink. Mater. Res. Express, v. 3(4), 045701, 2016. DOI: https://doi.org/10.1088/2053-1591/3/4/045701

SANTA-CRUZ, P. A. Dosímetro Imprimível para Radiação Ultravioleta. Depositor: UFPE. PI10030263. Patent deposit: 06 Ago. 2010. Issued: 21 Sept. 2021.

VAZ, E.C.R.; DOMINGUES, T.A.L.; SANTOS, T.E.C; MOURA, L.A; TAVARES, T.; MELO, L.F.M.; MELO, S.B.; SANTA-CRUZ, P.A. Personal monitoring of cutaneous vitamin D3 production using smartphone through printable UV molecular dosimetry strips, In: 1st Latin American Congress on Solid State Dosimetry and Radiation Measurements, 2021, Recife. Annals... 2021, 245-1. Available at: https://grupodoin.com/evento_1/abstract.htm Last accessed: 02 Mar. 2022.

GAMEIRO, C. G.; da SILVA JR., E. F.; ALVES JR., S.; de SÁ G. F.; SANTA-CRUZ, P. A. Molecular dosimeter developed from high efficient rare-earth complexes: UV-A, UV-B and UV-C responses Materials Science Forum, v. 315-317, p. 249-256, 1999. DOI: https://doi.org/10.4028/www.scientific.net/MSF.315-317.249

BATISTA H. J.; de ANDRADE A. V. M.; Longo R. L.; SIMAS A. M.; de SÁ G. F.; THOMPSON L. C. Synthesis, crystal structure determination and theoretical prediction of the structure and electronic spectrum of Eu(btfa)3 bipy. J. Luminescence, v. 72-4, p.159, 1997. DOI: https://doi.org/10.1016/S0022-2313(96)00158-5

SERRANO, M.A. Contribution of sun exposure to the vitamin D dose received by various groups of the Spanish population. Sci. Total Environ., v. 619–620, p. 545-551, 2018. DOI: https://doi.org/10.1016/j.scitotenv.2017.11.036

BOGH, M.K.B.; SCHMEDES, A. V.; PHILIPSEN, P. A.; THIEDEN, E.; WULF, H. C. Vitamin D production depends on ultraviolet-B dose but not on dose rate: A randomized controlled trial. Exp. Dermatol. v. 20, p. 14-18, 2010. DOI: https://doi.org/10.1111/j.1600-0625.2010.01201.x

JAGER, N.; SCHÖPE, J.; WAGENPFEIL, S.; BOCIONEK, P.; SATERNUS, R.; VOGT, T.; REICHRATH, J. The impact of UV-dose, body surface area exposed and other factors on cutaneous vitamin D synthesis measured as serum 25(OH)D concentration: systematic review and meta-analysis. Anticancer Res., v. 38 (2), p.1165-1171, 2018. DOI: https://doi.org/10.21873/anticanres.12336

POPE, S.J.; HOLICK, M.F.; MACKIN, S.; GODAR, D.E. Action spectrum conversion factors that change erythemally weighted to previtamin D3-weighted UV doses. Photochem. Photobiol. 84, 1277–1283, 2008. DOI: https://doi.org/10.1111/j.1751-1097.2008.00373.x

Commission Internationale de L'Eclairage (CIE) and World Meteorological Organization (WMO), 2014. CIE 209:2014. WMO/GWA Report No. 211. Rationalizing Nomenclature for UV Doses and Effects on Humans. CIE, Vienna. Available at: https://library.wmo.int/pmb_ ged/gaw_211_en.pdf.. Last accessed: 15 Dec. 2021.

MCKENZIE, R.L.; LILEY, J.B.; BJÖRN, L.O. UV radiation: balancing risks and benefits. Photochem. Photobiol., v.85, p. 88–98, 2009. DOI: https://doi.org/10.1111/j.1751-1097.2008.00400.x

FITZPATRICK, T.B. The validity and practicality of sun-reactive skin types I through VI. Arch. Dermatol., v. 124, p. 869–871, 1988. DOI: https://doi.org/10.1001/archderm.124.6.869

GODAR, D.E.; POPE, S.J.; GRANT, W.B.; HOLICK, M.F. Solar UV doses of adult Americans and vitamin D3 production. Dermato-Endocrinol., v.3, p.243–250, 2011. DOI: https://doi.org/10.4161/derm.3.4.15292

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Published

2022-07-21

How to Cite

Personal monitoring of cutaneous vitamin D3 production through a printable UV molecular dosimeter. Brazilian Journal of Radiation Sciences, Rio de Janeiro, Brazil, v. 10, n. 2A (Suppl.), 2022. DOI: 10.15392/bjrs.v10i2A.2032. Disponível em: https://www.bjrs.org.br/revista/index.php/REVISTA/article/view/2032.. Acesso em: 8 may. 2024.

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