The EDXRF Analysis to Monitor Iron Deficiency Anemia

Maria Paula de Oliveira Goes; Cibele Bugno Zamboni; Maria Gabriela Miquelino Benedito; Maria Regina Andrade Azevedo

doi:10.15392/2319-0612.2024.2671

Authors

Maria Paula de Oliveira Goes IPEN , Nuclear Energy Research Institute
Cibele Bugno Zamboni Instituto de Pesquisas Energéticas e Nucleares, 05508-000, São Paulo, São Paulo, Brazil. , Nuclear Energy Research Institute
Maria Gabriela Miquelino Benedito Instituto de Pesquisas Energéticas e Nucleares, 05508-000, São Paulo, São Paulo, Brazil , Nuclear Energy Research Institute
Maria Regina Andrade Azevedo Universidade Santo Amaro, 04743-030, São Paulo, São Paulo, Brazil , Universidade de Santo Amaro

DOI:

https://doi.org/10.15392/2319-0612.2024.2671

Keywords:

Whole Blood, Iron Deficiency Anemia, EDXRF, Iron concentration

Abstract

Iron Deficiency Anemia is a significant global issue, particularly affecting pregnant women and young children. Traditional methods of diagnosing iron-deficiency anemia generally require extensive and costly laboratory procedures. This study explores the feasibility of using portable Energy Dispersive X-ray Fluorescence (EDXRF) technology for assessing iron concentration in whole blood samples from donors diagnosed with iron deficiency anemia. The results indicated a marked decrease in iron levels in the blood samples from patients with anemia compared to the control group. The EDXRF technique demonstrated several advantages, including simplicity in sample collection, rapid measurement time, and low cost. This method is particularly promising for use in situations where biological material is limited, such as in pediatric practices for newborns. The study concludes that portable EDXRF technology is an effective and efficient tool for diagnosing iron deficiency anemia, potentially improving diagnostic accessibility and outcomes.

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