Influence of detectors efficiency normalization on small animal PET image quality

Authors

  • Mateus Gesulado Carneiro de Santana Centro de Desenvolvimento da Tecnologia Nuclear - CDTN/CNEN
  • Guilherme Cavalcante de Albuquerque Souza Centro de Desenvolvimento da Tecnologia Nuclear - CDTN/CNEN
  • Rodrigo Modesto Gadelha Gontijo Centro de Desenvolvimento da Tecnologia Nuclear - CDTN/CNEN
  • Bruno Melo Mendes Centro de Desenvolvimento da Tecnologia Nuclear - CDTN/CNEN
  • Andréa Vidal Ferreira

DOI:

https://doi.org/10.15392/bjrs.v7i3.861

Keywords:

Small Animal PET, Normalization, Image Quality, NEMA NU 4-2008

Abstract

LabPET GE 4 (a small animal positron emission tomograph) image acquisition is done by 1536 independents channels. Differences in the rate counting of each channel must be corrected so as not compromise image quality. Equipment user manual recommends that normalization of the detectors efficiency be made as often as possible and always whenever there are hardware or software parameters changes - included, but not limited to channels parameters adjustments, electronic cards replacements, channels activation or inactivation or software update. This work evaluates the normalization effects on the image quality parameters. PET image acquisition were performed using recommended parameters by the NEMA NU 4-2008 standards. Image was reconstructed in different ways using different normalization files. The tests performed indicated that the image quality parameters do not vary significantly with different normalization data. Therefore, a daily routine of normalizations is not justified, suggesting a periodical frequency of one month or more for this procedure.

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Author Biography

  • Andréa Vidal Ferreira
    Centro de Desenvolvimento da Tecnologia Nuclear - CDTN/CNEN

References

YAO R.; LECOMTE R.; CRAWFORD E. Small-Animal PET: What is it, and why do we need it? Journal of Nuclear Medicine Technology. 2011. Vol. 40 nº3, pp.157-165.

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GE Healthcare Technologies. Triumph Service Guide Technical Publication. Revision Draft 6, Copyright. Available at: <http://www.gehealthcare.com>. 2011.

TRETRAULT M. A., et al. System architecture of the LabPET small animal PET scanner. IEEE Transactions on Nuclear Science, 2008. Vol.55, pp. 2546-2550.

FONTAINE R., et al. The hardware and signal processing architecture of LabPETTM, a small animal APD-based digital PET scanner. IEEE Transactions on Nuclear Science, February 2009. Vol. 56, pp. 3-9.

Gamma Medica-Ideas, User Manual: Positron Emission Tomography (PET) Scanner Software - Manual for Acquisition and Processing of PET Images from the LABPET System. Software version: LABPET 1.12.0, (2010).

PMOD Tecnologies LCC, PMOD v.3.7. User Manual, (2015).

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Published

2019-07-04

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Section

Articles

How to Cite

Influence of detectors efficiency normalization on small animal PET image quality. Brazilian Journal of Radiation Sciences, Rio de Janeiro, Brazil, v. 7, n. 3, 2019. DOI: 10.15392/bjrs.v7i3.861. Disponível em: https://www.bjrs.org.br/revista/index.php/REVISTA/article/view/861. Acesso em: 2 may. 2025.