Considering the Figure of Merit as a parameter of optimization in Mammography: a case study of the performance in a CR and a DR system

Authors

  • Raíssa Xavier Contassot Hospital de Clínicas de Porto Alegre
  • Leonardo Catusso Universidade Federal de Uberlândia
  • Isabela Rocha Veiga da Silva Universidade Federal de Ciências da Saúde de Porto Alegre
  • Fabrício Nery Garrafiel Hospital São Lucas da PUCRS
  • Davi Silveira Azevedo Centro de Desenvolvimento da Tecnologia Nuclear
  • Cássio Costa Ferreira Hospital Universitário da UFS
  • Marcela Costa Alcântara Estácio Hospital Universitário da UFS
  • Felipe Amorim Santos Hospital Universitário da UFS
  • João Vinícius Batista Valença Universidade Federal de Ciências da Saúde de Porto Alegre

DOI:

https://doi.org/10.15392/2319-0612.2025.2765

Keywords:

figure of merit, optimization, image quality, mammography

Abstract

Mammography is an important examination for the early detection of breast cancer, and its use requires radiation protection considerations to ensure the lowest possible risk to the patient. The Figure of Merit (FOM) is a commonly used tool to quantify the relation between image quality and radiation dose. Higher FOM values suggest the most appropriate set of radiographic parameters to use in the examination. The objective of this study was to use the FOM as a metric for evaluating the optimization of two different clinical practices, one using a computed radiography (CR) system and the other using a digital radiography (DR) system. For both systems, three PMMA thicknesses were used (2, 4 and 7 cm), and acquisitions were performed at four voltage values commonly applied in clinical routines. Manual and automatic exposure modes were used for both systems. The CR system used Mo/Mo and Mo/Rh target-filter combinations, while the DR system used W/Rh and W/Ag. The image quality parameter used was the Contrast-to-Noise Ratio (CNR), and the considered dosimetric quantity was the Mean Glandular Dose (MGD). The FOMs presented relevant dependence on voltage and PMMA thicknesses, as well as variations with the different target-filter combinations. For both systems, when using 2 cm of PMMA, the FOM results were higher in the automatic acquisition mode. For 4 and 7 cm of PMMA, however, manual parameter adjustments became more relevant. These results reinforce the value of FOM as an important parameter in determining the most suitable acquisition settings for each analyzed equipment.

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References

[1] WCRF. World Cancer Research Fund International. Available at: https://www.wcrf.org/cancer-trends/worldwide-cancer-data/. Last access in: 06/27/2022.

[2] ACS. American Cancer Society. Available at: https://www.cancer.org/cancer/types/breast-cancer/about/how-common-is-breast-cancer.html. Last access in: 06/27/2022.

[3] INCA. Incidência. Rio de Janeiro, 2022. Disponível em: <https://www.gov.br/inca/pt-br/assuntos/gestor-e-profissional-de-saude/controle-do-cancer-de-mama/dados-e-numeros/incidencia>.

[4] OEFFINGER, K. C.; FONTHAM, E. T.; ETZIONI, R.; HERZIG, A.; MICHAELSON, J. S.; SHIH, Y. C. T.; WALTER, L. C.; CHURCH, T. R.; FLOWERS, C. R.; LAMONTE, S. J. Breast cancer screening for women at average risk: 2015 guideline update from the American Cancer Society. Jama, v. 314, n. 15, p. 1599-1614, 2015. DOI: https://doi.org/10.1001/jama.2015.12783

[5] GOLD, R. H.; BASSETT, L. W.; WIDOFF, B. E. Highlights from the history of mammography. Radiographics, v. 10, n. 6, p. 1111-1131, 1990. DOI: https://doi.org/10.1148/radiographics.10.6.2259767

[6] FREITAS, A. G.; KEMP, C.; LOUVEIRA, M. H.; FUJIWARA, S. M.; CAMPOS, L. F. Mamografia digital: perspectiva atual e aplicações futuras. Radiologia Brasileira, v. 39, p. 287-296, 2006. DOI: https://doi.org/10.1590/S0100-39842006000400012

[7] WOODARD, S.; MURRAY, A. Contrast-enhanced mammography: reviewing the past and looking to the future. In: Seminars in Roentgenology. WB Saunders, 2022, p. 126-133. DOI: https://doi.org/10.1053/j.ro.2021.12.001

[8] XAVIER, A.; BARROS, V. S.; KHOURY, H. J.; MELLO, F. A. Avaliação da dose glandular média em sistemas digitais e convencionais de mamografia. In: International Joint Conference RADIO, Sociedade Brasileira de Proteção Radiológica. 2014.

[9] KANAGA, K.; YAP, H.; LAILA, S.; SULAIMAN, T.; ZAHARAH, M.; SHANTINI, A. A critical comparison of three full field digital mammography systems using figure of merit. Med J Malaysia, v. 65, n. 2, p. 119-122, 2010.

[10] MERAD, A.; SAADI, S.; KHELASSI-TOUTAOUI, N. Comparison of two full field digital mammography systems: Image quality and radiation dose. In: AIP Conference Proceedings. AIP Publishing LLC, v. 1994, n. 1, p. 060008, 2018. DOI: https://doi.org/10.1063/1.5048169

[11] ACHO, S. N.; STOFILE, C.; MOLLER, M.; MORPHIS, M. Verification and optimisation of preselected exposure parameters in screening mammography: a central composite design methodology. Radiation Protection Dosimetry, v. 188, n. 3, p. 332-339, 2020. DOI: https://doi.org/10.1093/rpd/ncz291

[12] BUSHBERG, J. T.; BOONE, J. M. The essential physics of medical imaging. Lippincott Williams & Wilkins, 2011.

[13] NUNES, R.; BATISTA, W. Effect of target/filter combination on the mean glandular dose and contrast-detail threshold: A phantom study. Radiography, v. 27, n. 2, p. 272-278, 2021. DOI: https://doi.org/10.1016/j.radi.2020.08.007

[14] NIROSHANI, H.; NAKAMURA, T.; MICHIRU, N.; NEGISHI, T. Influence of double layer filter on mean glandular dose (MGD) and image quality in low energy image of contrast enhanced spectral mammography (LE-CESM). Radiography, v. 28, n. 2, p. 340-347, 2022. DOI: https://doi.org/10.1016/j.radi.2021.11.004

[15] AL KHALIFAH, K.; DAVIDSON, R.; ZHOU, A. Using aluminum for scatter control in mammography: preliminary work using measurements of CNR and FOM. Radiological Physics and Technology, v. 13, p. 37-44, 2020. DOI: https://doi.org/10.1007/s12194-019-00545-3

[16] SHARMA, R.; SHARMA, S.; SARKAR, P.; DATTA, D. Imaging and dosimetric study on direct flat-panel detector-based digital mammography system. Journal of Medical Physics, v. 43, n. 4, p. 255, 2018. DOI: https://doi.org/10.4103/jmp.JMP_64_18

[17] BORG, M.; BADR, I.; ROYLE, G. The use of a figure-of-merit (FOM) for optimisation in digital mammography: a literature review. Radiation Protection Dosimetry, v. 151, n. 1, p. 81-88, 2012. DOI: https://doi.org/10.1093/rpd/ncr465

[18] BORG, M.; KONSTANTINIDIS, A. Alternative figures-of-merit in digital mammography. Radiation Protection Dosimetry, v. 176, n. 4, p. 388-399, 2017. DOI: https://doi.org/10.1093/rpd/ncx022

[19] BALDELLI, P.; PHELAN, N.; EGAN, G. Investigation of the effect of anode/filter materials on the dose and image quality of a digital mammography system based on an amorphous selenium flat panel detector. The British journal of radiology, v. 83, n. 988, p. 290-295, 2010. DOI: https://doi.org/10.1259/bjr/60404532

[20] MORAIS, I. S.; SQUAIR, P. L.; TAVARES, M. S. N. Optimization of exposure parameters in digital mammography (CR) using figure of merit. Brazilian Journal of Radiation Sciences, v. 9, n. 1A, 2021. DOI: https://doi.org/10.15392/bjrs.v9i1A.1538

[21] FAUSTO, A. M.; LOPES, M.; SOUSA, M.; FURQUIM, T. A.; MOL, A. W.; VELASCO, F. G. Optimization of image quality and dose in digital mammography. Journal of digital imaging, v. 30, p. 185–196, 2017. DOI: https://doi.org/10.1007/s10278-016-9928-3

[22] PEREZ, A. M.; POLETTI, M. E.; TOMAL, A.; CORREIA, P. D.; PACIÊNCIA, R. D.; SILVA, M. C. Study of optimization in CR and DR digital mammography systems. Revista Brasileira de Física Médica, v. 11, n. 2, p. 11-15, 2017. DOI: https://doi.org/10.29384/rbfm.2017.v11.n2.p11-15

[23] PERRY, N.; BROEDERS, M.; DE WOLF, C.; TÖRNBERG, S.; HOLLAND, R.; VON KARSA, L. European guidelines for quality assurance in breast cancer screening and diagnosis. - summary document. Oncology in Clinical Practice, v. 4, n. 2, p. 74-86, 2008. DOI: https://doi.org/10.1093/annonc/mdm481

[24] IAEA. International Atomic Energy Agency. Dosimetry in diagnostic radiology: an international code of practice. 2007.

[25] PROTECTION, Radiological. ICRP Publication 103. Ann ICRP, v. 37, n. 2.4, p. 2, 2007.

[26] BRASIL. Resolução CNEN no 164/14. Norma CNEN NN-3.01 Diretrizes Básicas de Proteção Radiológica. Diário Oficial da República Federativa do Brasil, Ministério da Ciência e Tecnologia, Brasília, DF, 2005.

[27] DANCE, D.; SKINNER, C.; YOUNG, K.; BECKETT, J.; KOTRE, C. Additional factors for the estimation of mean glandular breast dose using the UK mammography dosimetry protocol. Physics in medicine & biology, v. 45, n. 11, p. 3225, 2000. DOI: https://doi.org/10.1088/0031-9155/45/11/308

[28] SCHNEIDER, C. A.; RASBAND, W. S.; ELICEIRI, K. W. NIH image to ImageJ: 25 years of image analysis. Nature methods, v. 9, n. 7, p. 671–675, 2012. DOI: https://doi.org/10.1038/nmeth.2089

[29] LAZZARO, M. V.; LUZ, R. M.; CAPAVERDE, A. S.; SILVA, A. M. M. Avaliação comparativa da qualidade da imagem em sistemas de radiologia computadorizada utilizando Imaging Plates com diferentes tempos de uso. Revista Brasileira de Física Médica (Online), 2015.

[30] SILVA, R. H. B. S. Estudo de otimização de sistemas mamográficos utilizando FOM (Figura de Mérito). 2017.

[31] IAEA. International Atomic Energy Agency. Quality assurance programme for digital mammography. 2011.

[32] BRASIL. Instrução Normativa - IN n° 92, de 27 de maio de 2021. Diário Oficial da União, Ministério da Saúde, Agência Nacional de Vigilância Sanitária, Diretoria Colegiada, 2021.

[33] OLIVEIRA, B. B.; OLIVEIRA, M. A.; PAIXÃO, L.; TEIXEIRA, M. H. A.; NOGUEIRA, M. S. Dosimetria e avaliação da qualidade da imagem em um sistema de radiografia direta. Radiologia Brasileira, v. 47, p. 361–367, 2014. DOI: https://doi.org/10.1590/0100-3984.2013.1876

[34] JAKUBIAK, R.; GAMBA, H.; NEVES, E.; PEIXOTO, J. Image quality, threshold contrast and mean glandular dose in CR mammography. Physics in Medicine & Biology, v. 58, n. 18, p. 6565, 2013. DOI: https://doi.org/10.1088/0031-9155/58/18/6565

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Published

2025-02-14

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How to Cite

Considering the Figure of Merit as a parameter of optimization in Mammography: a case study of the performance in a CR and a DR system. Brazilian Journal of Radiation Sciences, Rio de Janeiro, Brazil, v. 13, n. 1, p. e2765, 2025. DOI: 10.15392/2319-0612.2025.2765. Disponível em: https://www.bjrs.org.br/revista/index.php/REVISTA/article/view/2765. Acesso em: 2 may. 2025.