Parameters for Validating a Spectrometric System with Itinerant NaI(Tl) in the Ativimeter’s Calibration

Dayana Azeredo Conceição; J. U.  Delgado; O.L.T.  Filho

doi:10.15392/2319-0612.2024.2754

Authors

Dayana Azeredo Conceição Instituto de Radioproteção e Dosimetria IRD/CNEN
J. U. Delgado Instituto de Radioproteção e Dosimetria IRD/CNEN, RJ, Brazil
O.L.T. Filho Instituto de Radioproteção e Dosimetria IRD/CNEN, RJ, Brazil

DOI:

https://doi.org/10.15392/2319-0612.2024.2754

Keywords:

NaI(TI), method validations, activimeter calibrations, performance indicator parameters

Abstract

In radiopharmaceutical production centers and nuclear medicine services, short half-life radionuclides are essential. They have been used as radiotracers since their use increased significantly and aroused the interest of national metrology laboratories, which are responsible for providing traceability to radioactive standards. Therefore, knowledge of the activity of administered radiopharmaceuticals must be obtained accurately. However, their short half-lives prevent the provision of traceability. To overcome these obstacles, an itinerant system based on a NaI(Tl)-type scintillator detector is being developed at the National Laboratory for Ionizing Radiation Metrology (LNMRI). This work aims to show the schematic arrangement of the system developed to calibrate activimeters, as well as the tests and experimental comparisons carried out in this study using performance indicator parameters to characterize and validate the itinerant NaI(Tl) detection system in the calibration of activimeters.

Downloads

Download data is not yet available.

References

[1] IAEA, Quantitative Nuclear Medicine Imaging: Concepts, Requirements and Methods, International Atomic Energy Agency, Human Health Reports No 9,2014.

[2] SAHA, G. B., Fundamentals of Nuclear Pharmacy. Fifth Edition. Springer, 2004.

[3] C. MICHOTTE, C.; NONIS, M.; ARENILLAS, P.; CERUTTI, G.; DA SILVA. J.C.; ALBERTO LIMA DA CRUZ, PAULO ; SIMÕES MOREIRA, DENISE ; IWAHARA, AKIRA ; DELGADO, J.U; POLEDNA, ROBERTO ; LINS DA SILVA, RONALDO ; EDUARDO DE OLIVEIRA, ANTÔNIO ; DOS SANTOS GOMES, RÉGIO, Activity measurements of the radionuclide 99m Tc for the CNEA, Argentina and the LNMRI/IRD, Brazil in the ongoing comparison BIPM.RI(II)-K4.Tc-99m, , Metrologia (Online), v. 50, p. 06023-06023,2013. DOI: https://doi.org/10.1088/0026-1394/50/1A/06023

[4] ISO/20042, Measurement of radioactivity — Gamma-ray emitting radionuclides — Generic test method using gamma-ray spectrometry,2019.

[5] AZEREDO, D., DELGADO, J.U., OLIVEIRA, A.E. Viabilidade para implantação de um sistema itinerante de referência para medição de radiofármacos no LNMRI. CBMRI, Rio de Janeiro.

[6] CHERRY, S.R., SORENSON, J.A., PHELPS, M.E., 2012, Physics in nuclear medicine, 4th ed., Philadelphia, Elsevier, 2020. DOI: https://doi.org/10.1016/B978-1-4160-5198-5.00001-0

[7] ISO/17025, Requisitos gerais para a competência de laboratórios de ensaio e calibração. 3° edição, ABNT NBR, Rio de janeiro, RJ. ISBN:978-85-07-07368-0,2017.

[8] Osprey, Universal Digital MCA Tube Base, 7066438E. User’s Manual, 2012.

[9] CACAIS, F.L., DELGADO, J.U., LOAYZA,V. M., Uncertainty evaluation of a modified elimination weighing for source preparation, Brazilian Congress on Metrology, IOP Conf. Series: Journal of Physics: Conf. Series 975 (2018) 012057, doi :10.1088/1742-6596/975/1/012057, 2017. DOI: https://doi.org/10.1088/1742-6596/975/1/012057

[10] VIM, Vocabulário Internacional de Metrologia: Conceitos fundamentais e gerais e termos associados (VIM 2012). Duque de Caxias, RJ : INMETRO, 94 p,2012.

[11] ISO 11929, Determination of the characteristic limits (decision threshold, detection limit and limits of the confidence interval) for measurements of ionizing radiation — Fundamentals and application.