Calibration and evaluation of the MTS-N dosimeter for absorbed dose measurement in blood components

Authors

  • Lorena Fonseca Centro de Desenvolvimento da Tecnologia Nuclear
  • Daniel Silva Calheiro Universidade Federal de Minas Gerais https://orcid.org/0000-0001-6822-3065
  • Amir Mesquita Centro de Desenvolvimento da Tecnologia Nuclear
  • Thêssa Alonso Centro de Desenvolvimento da Tecnologia Nuclear
  • Peterson Squair Centro de Desenvolvimento da Tecnologia Nuclear

DOI:

https://doi.org/10.15392/2319-0612.2024.2502

Keywords:

Blood irradiation, Dosimetry, Calibration, Thermoluminescence

Abstract

The use of ionizing radiation has significantly expanded, particularly in the healthcare sector, where the irradiation of blood components prevents transfusion-associated graft-versus-host disease (TA-GvHD). The ISO ASTM 51939:2017 standard establishes a minimum dose of 25 Gy for this procedure, requiring a precise and traceable dosimetric system. This study investigates the calibration of MTS-N thermoluminescent dosimeters at the Gamma Irradiation Laboratory (LIG) of CDTN, which currently uses radiochromic films for routine dosimetry. The dosimeters were calibrated using a RISØ TL/OSL DA-20 reader, and the results indicated that doses above 5 Gy caused reader saturation, distorting the TL emission curve. The introduction of attenuating filters maintained linearity up to 25 Gy, and the calibration coefficient was determined as 6.774×10⁻⁷ Gy/Count, confirming the system’s suitability for dosimetry in blood irradiation at LIG/CDTN.

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References

[1] Pino, E. S., Giovedi, C. "Ionizing Radiation and Its Applications in Industry," UNILUS Teaching and Research Journal, no. 2, vol. 2, Jan/Jun 2015.

[2] American Association Blood Bank. Irradiation. Available at: http://www.aabb.org/advocacy/regulatorygovernment/irradiation/Pages/default.aspx. Accessed on: 27 Feb. 2024.

[3] ALAN, H. Y. et al. A study on quality control check of dose distribution in blood bags irradiated by 137Cs source blood irradiator by using EBT3 radiochromic film dosimetry. Radiation Physics and Chemistry, v. 214, p. 111303, 2024. DOI: https://doi.org/10.1016/j.radphyschem.2023.111303

[4] ISO/ASTM. (2017). ISO/ASTM 51939:2017 - Standard Practice for Blood Irradiation Dosimetry.

[5] CALHEIRO, D. S. et al. Mapping absorbed dose distribution in containers of blood and blood components using radiochromic dosimeters irradiated in an industrial irradiator. Radiation Physics and Chemistry, v. 222, p. 111797, 2024. DOI: https://doi.org/10.1016/j.radphyschem.2024.111797

[6] GRASSO, S. et al. Absorbed dose evaluation of a blood irradiator with alanine, TLD-100 and ionization chamber. Applied Radiation and Isotopes, v. 200, p. 110981, 2023. DOI: https://doi.org/10.1016/j.apradiso.2023.110981

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Published

2025-04-14

How to Cite

Calibration and evaluation of the MTS-N dosimeter for absorbed dose measurement in blood components. Brazilian Journal of Radiation Sciences, Rio de Janeiro, Brazil, v. 12, n. 4A (Suppl.), p. e2502, 2025. DOI: 10.15392/2319-0612.2024.2502. Disponível em: https://www.bjrs.org.br/revista/index.php/REVISTA/article/view/2502. Acesso em: 1 may. 2025.