Development of alternative methodology for normalization of the small animals PET scanner of LIM/CDTN
DOI:
https://doi.org/10.15392/2319-0612.2024.2360Keywords:
Normalization, Ge-68 source, 18F-FDG, Small Animal PET ScannerAbstract
Normalization is a step taken to correct variations in count rates between detection channels of small animals PET scanners. In general, in laboratory practice, normalization is performed using a commercial source of germanium 68. Given the half-life of the Ge-68 isotope, the normalization source must be replaced every two years at most, which generates a significant spent for the Laboratory. The objective of this work was to develop and test an alternative rechargeable source to be used on normalization routine. The results indicated that the rechargeable source (18F-FDG) can be used to replace the commercial source.
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SAHA, G. B. Basics of PET imaging, Second Edition. 2. ed. Cleveland: Springer, 2010. 244 p. ISBN 978-1-4419-0804-9
GE Healthcare Technologies, Triumph Service Guide Technical Publication. Revision Draft 6, Copyright. Available in: <http://www.gehealthcare.com>. 2011.
QRM. Micro-PET IQ Phantom, NEMA NU4, for performance evaluation of Micro-PET systems according to NEMA NU 4 , available in www.qrm.de, consulted in 06/13/2023.
NEMA - National Electrical Manufacturers Association. Performance Measurements of Small Animal Positron Emission Tomographs. Rosslyn VA; 2008 Standards Publication NU 4-2008
GONTIJO, R. M. G. Image quality evaluation of a small animal PET scanner. Brazilian Journal of Radiation Sciences, 08-01(2020)
BELCARI, N. et al., NEMA NU-4 Performance Evaluation of the IRIS PET/CT Preclinical Scanner. IEEE Transactions on Nuclear Science. 2017. v. 1. p. 301-309. 2017. DOI: https://doi.org/10.1109/TRPMS.2017.2707300
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